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Products Details
Product Description
– Ertapenem (MK-0826) is a broad spectrum and long acting β-lactam antibiotic. Ertapenem has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract[1][2].
Web ID
– HY-A0294
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C22H25N3O7S
Citations
– J Antimicrob Chemother. 2023 Jul 31;dkad229.|Biomed Res Int. 2018 Jul 2;2018:3579832. |J Antimicrob Chemother. 2020 Jul 1;75(7):1850-1858.|Nat Commun. 2021 Jul 22;12(1):4461.|Nat Commun. 2022 Mar 2;13(1):1116.
References
– [1]Kenneth E Aldridge. Ertapenem (MK-0826), a new carbapenem: comparative in vitro activity against clinically significant anaerobes. Diagn Microbiol Infect Dis. 2002 Oct;44(2):181-6.|[2]C J Gill, et al. In vivo activity and pharmacokinetic evaluation of a novel long-acting carbapenem antibiotic, MK-826 (L-749,345). Antimicrob Agents Chemother. 1998 Aug;42(8):1996-2001.
CAS Number
– 153832-46-3
Molecular Weight
– 475.51
SMILES
– O=C(C(N12)=C(S[C@@H]3CN[C@H](C(NC4=CC=CC(C(O)=O)=C4)=O)C3)[C@H](C)[C@]2([H])[C@@H]([C@H](O)C)C1=O)O
Clinical Information
– Launched
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Antibiotic;Bacterial
Isoform
– β-lactam
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
