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Products Details
Product Description
– ERRγ Inverse Agonist 1 (Compound 12) is a potent, selective and orally bioavailable Estrogen-related Receptor grammar (ERRγ) inverse agonist, with an IC50 of 40 nM[1].
Web ID
– HY-114411
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C30H38Cl2N2O2
References
– [1]Kim J, et al. Discovery of Potent, Selective, and Orally Bioavailable Estrogen-Related Receptor-γ Inverse Agonists To Restore the Sodium Iodide Symporter Function in Anaplastic Thyroid Cancer. J Med Chem. 2019 Feb 28;62(4):1837-1858.
CAS Number
– 2316832-86-5
Molecular Weight
– 529.54
SMILES
– OC1=CC=CC(/C(C2=CC=C(N3CCN(C(C)C)CC3)C=C2)=C(C4=CC=CC=C4)CCCO)=C1.[H]Cl.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in H2O
Target
– Estrogen Receptor/ERR
Isoform
– ERRβ;ERRγ;ERα
Pathway
– Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
