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Products Details
Product Description
– ERK2 IN-1 is a selective ERK2 inhibitor with an IC50 of 7 nM[1].
Web ID
– HY-112300
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C36H34FN7O2S
References
– [1]Boga SB, Discovery of 3(S)-thiomethyl pyrrolidine ERK inhibitors for oncology. Bioorg Med Chem Lett. 2018 Jun 15;28(11):2029-2034.
CAS Number
– 1093061-47-2
Molecular Weight
– 647.76
SMILES
– FC1=CC=C(C2=NNC3=C2C=C(NC([C@@]4(SC)CN(CC(N5CCC(C6=CC=C(C7=NC=CC=N7)C=C6)=CC5)=O)CC4)=O)C=C3)C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ERK
Isoform
– ERK2
Pathway
– MAPK/ERK Pathway;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
