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Products Details
Product Description
– ERK-IN-7 (Example 10), an analogue of SHR2415 (HY-151367), is a potent ERK inhibitor with IC50 of 5 nM and 7 nM against ERK1 and ERK2, respectively[1].
Web ID
– HY-153350
Shipping
– Room temperature
Molecular Formula
– C22H20ClN7O2
References
– [1]Xin Li, et al. Pyrroloheterocyclic derivative, preparation method therefor, and application thereof in medicine. Patent WO2020200069A1.
CAS Number
– 2494010-63-6
Molecular Weight
– 449.89
SMILES
– O=C1N2C(CN1[C@@H](C3=CC(Cl)=CC=C3)CO)=CC(C4=NC(NC5=CC=NN5C)=NC=C4)=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ERK
Isoform
– ERK1;ERK2
Pathway
– MAPK/ERK Pathway;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
