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Products Details
Product Description
– Eritoran is a Toll-like receptor 4 (TLR4) antagonist. Eritoran protects mice against lethal influenza virus infection, such as Ebola virus (EBOV), Marburg virus (MARV). Eritoran decreases the level of granulocytosis, may alleviate the severity of the “cytokine storm”. Eritoran inhibits pathogenesis of filovirus infection[1].
Web ID
– HY-105070
Shipping
– Room temperature
Molecular Formula
– C66H126N2O19P2
References
– [1]Younan P, et al. The Toll-Like Receptor 4 Antagonist Eritoran Protects Mice from Lethal Filovirus Challenge. mBio. 2017 Apr 25;8(2):e00226-17.
CAS Number
– 185955-34-4
Molecular Weight
– 1313.66
SMILES
– CCCCCCC[C@@H](OC)CCO[C@@H]1[C@H]([C@@H](O[C@H](COC)[C@H]1OP(O)(O)=O)OC[C@@H]2[C@H]([C@@H]([C@@H](NC(CC(CCCCCCCCCCC)=O)=O)[C@@H](OP(O)(O)=O)O2)OCCCCCCCCCC)O)NC(CCCCCCCCC/C=CCCCCCC)=O
Clinical Information
– Phase 3
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– EBV;Toll-like Receptor (TLR)
Isoform
– TLR4
Pathway
– Anti-infection;Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
