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Products Details
Product Description
– ER degrader 5 is a potent estrogen receptor (ER) degrader. ER degrader 5 shows anti-proliferation activity. ER degrader 5 can be used for the research of breast cancer[1].
Web ID
– HY-149970
Shipping
– Room temperature
Molecular Formula
– C26H18F2O4S
References
– [1]Lu Y, et, al. Design, synthesis and biological evaluation of fluorinated selective estrogen receptor degraders (FSERDs) — A promising strategy for advanced ER positive breast cancer. Eur J Med Chem. 2023 May 5;253:115324.
CAS Number
– 2913192-47-7
Molecular Weight
– 464.48
SMILES
– O=C(C1=C(C=C(C=C1C)F)C)C(SC2=CC(F)=CC=C23)=C3OC4=CC=C(C=C4)/C=C/C(O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Estrogen Receptor/ERR
Pathway
– Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
