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Product Description
– ER degrader 1 is a potent degrader of estrogen receptor (ER). The estrogen signaling system plays an important role in regulating cell growth, differentiation and apoptosis. ER degrader 1 has the potential for the research of cancer diseases (extracted from patent WO2021139756A1, compound 11)[1].
Web ID
– HY-142925
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C26H32F4N4O3
References
– [1]Fanglong Yang, et al. Tricyclic tetrahydroisoquinoline derivatives, their preparation methods and their application in medicine. Patent WO2021139756A1.
CAS Number
– 2667015-33-8
Molecular Weight
– 524.55
SMILES
– OCC(F)(F)CN1[C@@](C2=C(C=C(C=N2)N[C@@H]3CN(CC3)CCCF)F)([H])C4=C(C[C@H]1C)C=C5C(OCO5)=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Estrogen Receptor/ERR
Pathway
– Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
