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Eprosartan
SKU
HY-117743-10 mg
Category Reference compound
Tags Angiotensin Receptor, Cardiovascular Disease, GPCR/G Protein
$51 – $88
Products Details
Product Description
– Eprosartan (SKF-108566J free base) is a selective, competitive, nonpeptid and orally active angiotensin II receptor antagonist, used as an antihypertensive. Eprosartan binds angiotensin II receptor with IC50s of 9.2 nM and 3.9 nM in rat and human adrenal cortical membranes, respectively [1].
Web ID
– HY-117743
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C23H24N2O4S
References
– [1]R M Edwards, et al. Pharmacological characterization of the nonpeptide angiotensin II receptor antagonist, SK&F 108566. J Pharmacol Exp Ther. 1992 Jan;260(1):175-81.
CAS Number
– 133040-01-4
Molecular Weight
– 424.51
Compound Purity
– 95.29
SMILES
– O=C(C1=CC=C(C=C1)CN2C(/C=C(CC3=CC=CS3)/C(O)=O)=CN=C2CCCC)O
Clinical Information
– Launched
Research Area
– Cardiovascular Disease
Solubility
– DMSO : 125 mg/mL (ultrasonic)
Target
– Angiotensin Receptor
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.