Epibetulinic acid

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Products Details

Product Description

– Epibetulinic acid exhibits potent inhibitory effects on NO and prostaglandin E2 (PGE2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin with IC50s of 0.7 and 0.6 μM, respectively. Anti-inflammatory activity[1].

Web ID

– HY-N0223

Storage Temperature

– -20°C (Powder, protect from light)

Shipping

– Blue Ice

Applications

– Metabolism-sugar/lipid metabolism

Molecular Formula

– C30H48O3

References

– [1]Reyes CP, et al. Activity of lupane triterpenoids from Maytenus species as inhibitors of nitric oxide and prostaglandin E2. Bioorg Med Chem. 2006 Mar 1;14(5):1573-9.

CAS Number

– 38736-77-5

Molecular Weight

– 456.70

Compound Purity

– 98.0

SMILES

– CC1(C)[C@H](O)CC[C@]2(C)[C@@]3([H])CC[C@]4([H])[C@@]5([H])[C@H](C(C)=C)CC[C@@](C(O)=O)5CC[C@](C)4[C@@](C)3CC[C@@]12[H]

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology; Endocrinology

Solubility

– DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)

Target

– NO Synthase;Prostaglandin Receptor

Isoform

– EP

Pathway

– GPCR/G Protein;Immunology/Inflammation

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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