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Products Details
Product Description
– EP12 is a c-Myc inhibitor. EP12 is a c-Myc G4 stabilizer. EP12 induces apoptosis and DNA damage in multiple myeloma cells. EP12 disrupts the nuclear translocation of P65/P50 by interfering with the NF-κB signaling pathway. EP12 inhibits multiple myeloma growth[1].
Web ID
– HY-149513
Shipping
– Room temperature
Molecular Formula
– C26H22FN3O2
References
– [1]Yao R, et al. Novel c-Myc G4 stabilizer EP12 promotes myeloma cytotoxicity by disturbing NF-κB signaling. Exp Cell Res. 2023 Oct 1;431(1):113759.
CAS Number
– 2882916-73-4
Molecular Weight
– 427.47
SMILES
– FC1=CC=C(C2=CC(C3=NC4=C(C=CC=C4)N3CCOC5=CC(C)=CC(C)=C5)=NO2)C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;c-Myc
Pathway
– Apoptosis
Product type
– Reference compound
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