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Encephalitic alphavirus-IN-1
SKU
HY-145842-Get quote
Category Reference compound
Tags Anti-infection, Infection; Neurological Disease, Virus Protease
Products Details
Product Description
– Encephalitic alphavirus-IN-1 has antiviral activity for VEEV and EEEV with EC50s of 0.24 μM and 0.16 μM, respectively. Encephalitic alphavirus-IN-1 has robust mouse plasma stability, and no obvious cytotoxicity[1].
Web ID
– HY-145842
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C27H25FN6O2
References
– [1]Ryan MC, et al. Piperazinobenzodiazepinones: New Encephalitic Alphavirus Inhibitors via Ring Expansion of 2-Dichloromethylquinazolinones. ACS Med Chem Lett. 2022;13(4):546-553. Published 2022 Mar 14.
Molecular Weight
– 484.52
SMILES
– [H]C12C(N(CCN2C)C)=NC3=C(C=C(C=C3C(N1C4=CC(F)=C(C=C4)OC)=O)C#N)C5=CC=C(N=C5)C
Clinical Information
– No Development Reported
Research Area
– Infection; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Virus Protease
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.