Products Details

Product Description

– Encephalitic alphavirus-IN-1 has antiviral activity for VEEV and EEEV with EC50s of 0.24 μM and 0.16 μM, respectively. Encephalitic alphavirus-IN-1 has robust mouse plasma stability, and no obvious cytotoxicity[1].

Web ID

– HY-145842

Shipping

– Room temperature

Applications

– COVID-19-anti-virus

Molecular Formula

– C27H25FN6O2

References

– [1]Ryan MC, et al. Piperazinobenzodiazepinones: New Encephalitic Alphavirus Inhibitors via Ring Expansion of 2-Dichloromethylquinazolinones. ACS Med Chem Lett. 2022;13(4):546-553. Published 2022 Mar 14.

Molecular Weight

– 484.52

SMILES

– [H]C12C(N(CCN2C)C)=NC3=C(C=C(C=C3C(N1C4=CC(F)=C(C=C4)OC)=O)C#N)C5=CC=C(N=C5)C

Clinical Information

– No Development Reported

Research Area

– Infection; Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Virus Protease

Pathway

– Anti-infection

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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