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Enarodustat
$94 – $825
Products Details
Product Description
– Enarodustat is a potent and orally active hypoxia-inducible factor prolyl hydroxylase inhibitor, with an EC50 of 0.22 μM. Enarodustat has the potential for renal anemia treatment.
Web ID
– HY-109057
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C17H16N4O4
References
– [1]Ogoshi Y, et al. Discovery of JTZ-951: A HIF Prolyl Hydroxylase Inhibitor for the Treatment of Renal Anemia. ACS Med Chem Lett. 2017 Nov 20;8(12):1320-1325.
CAS Number
– 1262132-81-9
Molecular Weight
– 340.33
Compound Purity
– 99.94
SMILES
– O=C(C(C1=NC=NN1C(CCC2=CC=CC=C2)=C3)=C3O)NCC(O)=O
Clinical Information
– Launched
Research Area
– Metabolic Disease
Solubility
– DMSO : 83.33 mg/mL (ultrasonic)
Target
– HIF/HIF Prolyl-Hydroxylase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
