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Elliptinium (acetate)
Products Details
Product Description
– Elliptinium acetate (NSC 264137) is a DNA intercalating agent that is highly cytotoxic to L1 210 cells and covalently binds to nucleic acids from L1210 cells. Elliptinium acetate can be used in cancer research, particularly in metastatic breast cancer[1][2].
Web ID
– HY-16189
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H20N2O3
References
– [1]Dugue B, et al. Covalent binding of elliptinium acetate (NSC 264137) to nucleic acids of L1210 cells in culture. Cancer Res. 1986 Aug;46(8):3828-33.|[2]Arteaga CL, et al. Elliptinium, a DNA intercalating agent with broad antitumor activity in a human tumor cloning system. Eur J Cancer Clin Oncol. 1987 Nov;23(11):1621-6.
CAS Number
– 58337-35-2
Molecular Weight
– 336.38
SMILES
– O=C(C)[O-].OC1=CC=C2NC3=C(C)C4=C(C=[N+](C)C=C4)C(C)=C3C2=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– DNA Stain
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
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