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Elimusertib-d3
SKU
HY-101566S-1 mg
Category Isotope-Labeled Compounds
Tags ATM/ATR, Cancer, Cell Cycle/DNA Damage;PI3K/Akt/mTOR
$400 – $2,100
Products Details
Product Description
– Elimusertib-d3 (BAY 1895344-d3) is the deuterium labeled Elimusertib (BAY 1895344). Elimusertib is a potent, orally active and selective ATR inhibitor and has anti-tumor activity[1].
Web ID
– HY-101566S
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C20H18D3N7O
References
– [1]Ulrich T. Luecking, et al. Abstract 983: Identification of potent, highly selective and orally available ATR inhibitor BAY 1895344 with favorable PK properties and promising efficacy in monotherapy and combination in preclinical tumor models. Cancer Research. July 2017 Volume 77, Issue 13 Supplement.
Molecular Weight
– 378.45
Compound Purity
– 98.94
SMILES
– C[C@H]1N(C2=CC(C3=CC=NN3C([2H])([2H])[2H])=C(C=CN=C4C5=CC=NN5)C4=N2)CCOC1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ATM/ATR
Pathway
– Cell Cycle/DNA Damage;PI3K/Akt/mTOR
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.