Download Files:
eIF4A3-IN-8
SKU
HY-33838-100 mg
Category Reference compound
Tags Cancer, Cell Cycle/DNA Damage, Eukaryotic Initiation Factor (eIF)
$50 – $95
Products Details
Product Description
– eIF4A3-IN-8 is a selective ATP-competitive eukaryotic initiation factor 4A3 (eIF4A3) inhibitor. eIF4A3-IN-8 can serve as a valuable chemical probe to elucidate the detailed function of eIF4A3 and EJC (exon junction complex)[1].
Web ID
– HY-33838
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C10H9NO2
References
– [1]Ito M, et al. Discovery of selective ATP-competitive eIF4A3 inhibitors. Bioorg Med Chem. 2017 Apr 1;25(7):2200-2209.
CAS Number
– 18474-59-4
Molecular Weight
– 175.18
Compound Purity
– 99.98
SMILES
– O=C(C(N1)=CC2=C1C=C(C)C=C2)O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Eukaryotic Initiation Factor (eIF)
Isoform
– eIF4
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.