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Products Details
Product Description
– eIF4A3-IN-5 is a potent inhibitor of eukaryotic initiation factor 4A (eIF4A), such as eIF4AI and eIF4AII. eIF4A3-IN-5 has the potential for the research of eIF4A dependent diseases, including the research of cancer (extracted from patent US20170145026A1)[1].
Web ID
– HY-145359
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C26H22N2O7
References
– [1]Justin T. Ernst, et al. Eif4a-inhibiting compounds and methods related thereto. Patent US20170145026A1.
CAS Number
– 2100145-31-9
Molecular Weight
– 474.46
SMILES
– O[C@]12[C@](OC3=CC(OC)=NC(OC)=C32)(C4=CC=C(C=C4)C#N)[C@@](C5=CC=CC=C5)([H])[C@H]([C@H]1O)C(O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Eukaryotic Initiation Factor (eIF)
Isoform
– eIF4
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
