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eIF4A3-IN-4
$478
Only 1000 item(s) left in stock.
Products Details
Product Description
– eIF4A3-IN-4 is a novel eIF4A inhibitor with an IC50 value of 8.6 μM.
Web ID
– HY-139872
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C24H20N2O5
References
– [1]Zerio CJ, et al. Discovery of an eIF4A Inhibitor with a Novel Mechanism of Action. J Med Chem. 2021 Nov 11;64(21):15727-15746.
CAS Number
– 2861994-92-3
Molecular Weight
– 416.43
SMILES
– OC(C1=C2C(C=CC([N+]([O-])=O)=C2)=NC(C3=CC=C(C4=CC=C(CCCC)C=C4)O3)=C1)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Eukaryotic Initiation Factor (eIF)
Isoform
– eIF4
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
