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Products Details
Product Description
– EGFR-IN-88 (Compound 4i) is an EGFR inhibitor (IC50: 87 nM). EGFR-IN-88 shows cytotoxicity against A549 cell with an IC50? of 3.902? μM. EGFR-IN-88 can induce cell apoptosis[1].
Web ID
– HY-156033
Shipping
– Room temperature
Molecular Formula
– C22H18Cl2N4O2S
References
– [1]Ali SH, et al. Design, synthesis, and molecular docking studies of novel quinoxaline derivatives as anticancer agents. Chem Biol Drug Des. 2023 Aug;102(2):303-315.
CAS Number
– 2944452-34-8
Molecular Weight
– 473.37
SMILES
– O=C(C1=CC=C(Cl)C=C1Cl)CSC2=NN=C(C3=CC=C4N=C(CC)C(CC)=NC4=C3)O2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;EGFR
Pathway
– Apoptosis;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
