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Products Details
Product Description
– EGFR-IN-85 (Compound 1) is an EGFR inhibitor. EGFR-IN-85 has IC50 value of 0.19 μM for EGFRvâ…¢ phosphorylation. EGFR-IN-85 can suppress EGFR signaling within tumors. EGFR-IN-85 can be used for Glioblastoma (GBM) research[1].
Web ID
– HY-111452
Shipping
– Room temperature
Molecular Formula
– C26H30N8O2
References
– [1]Zhao J, et al. (1h-pyrrolo[2,3-b]pyridin-1-yl)pyrimidin-2-yl-amino-phenyl–acrylamide inhibitors of egfr for use in the treatment of brain tumors. The United States, WO2022271861 A1. 2022-12-29.
CAS Number
– 1956378-29-2
Molecular Weight
– 486.57
SMILES
– O=C(NC1=CC(NC2=NC=CC(N3C=CC4=C3N=CC=C4)=N2)=C(C=C1N(CCN(C)C)C)OC)C=C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– EGFR
Pathway
– JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
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