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Products Details
Product Description
– EGFR-IN-84 (Compound 6g) is an EGFR inhibitor (IC50: 24 nM). EGFR-IN-84 inhibits A549 cell growth (IC50: 1.537 μM). EGFR-IN-84 can be used for research of lung cancer[1].
Web ID
– HY-155200
Shipping
– Room temperature
Molecular Formula
– C25H20N6O3S2
References
– [1]Kurban B, et al. Synthesis and Anticancer Activities of Pyrazole-Thiadiazole-Based EGFR Inhibitors. ACS Omega. 2023 Aug 17;8(34):31500-31509.
Molecular Weight
– 516.59
SMILES
– O=C(CSC1=NN=C(NC2=CC=CC=C2)S1)N(C(C3=CC=C([N+]([O-])=O)C=C3)C4)N=C4C5=CC=CC=C5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– EGFR
Pathway
– JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
