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Products Details
Product Description
– EGFR-IN-75 is an EGFRWT and EGFRT790M inhibitor with IC50 values of 0.28 μM and 5.02 μM, respectively. EGFR-IN-75 shows anticancer and antioxidant activity[1].
Web ID
– HY-152144
Shipping
– Room temperature
Molecular Formula
– C10H6N6S2
References
– [1]Sanaa A Ahmed, et al. Thieno[2,3- b]thiophene Derivatives as Potential EGFRWT and EGFRT790M Inhibitors with Antioxidant Activities: Microwave-Assisted Synthesis and Quantitative In Vitro and In Silico Studies. ACS Omega. 2022 Dec 3;7(49):45535-45544.
Molecular Weight
– 274.32
SMILES
– NC1=NC=NC2=C1SC3=C2C4=C(C(N)=NC=N4)S3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– EGFR
Isoform
– EGFR/ErbB1/HER1
Pathway
– JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
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