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Products Details
Product Description
– EGFR-IN-68 (Compound 8d) is a potent EGFR inhibitor with an IC50 of 0.33 μM. EGFR-IN-68 shows anticancer activity[1].
Web ID
– HY-147997
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C24H22N2O
References
– [1]George RF, et al. Some 1,3,5-trisubstituted pyrazoline derivatives targeting breast cancer: Design, synthesis, cytotoxic activity, EGFR inhibition and molecular docking. Bioorg Chem. 2020 Jun;99:103780.
CAS Number
– 2416925-03-4
Molecular Weight
– 354.44
SMILES
– COC1=CC=C(N2N=C(C3=CC=CC=C3)CC2/C=C/C4=CC=CC=C4)C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– EGFR
Pathway
– JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
