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Products Details
Product Description
– EGFR-IN-23 is a potent EGFR TKI (tyrosine kinase inhibitor) with an IC50 of 8.05 nM for BaF3/EGFR-DEL19/T790M/C797S cell (WO2021244502A1, compound 8)[1].
Web ID
– HY-142680
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C36H44BrN10O3P
References
– [1]Polyaryl compound and use. WO2021244502A1.
CAS Number
– 2747133-37-3
Molecular Weight
– 775.68
SMILES
– CN1N=CC(C2=C(N3CCC(CN4CCOCCC4)CC3)C=C(OC)C(NC5=NC=C(Br)C(NC6=CC=C7N=CC=NC7=C6P(C)(C)=O)=N5)=C2)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– EGFR
Pathway
– JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
