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Products Details
Product Description
– EGFR-IN-15 (compound I-005) is a EGFR inhibitor with an IC50 of 4 nM. EGFR-IN-15 can be used for oncological diseases research[1].
Web ID
– HY-138746
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C24H25BrN6O2
References
– [1]Harald Engelhardt, et al. New macrocyclic compounds and derivatives as egfr inhibitors. WO2020260252A1.
CAS Number
– 2573869-16-4
Molecular Weight
– 509.40
SMILES
– C[C@H]1CN2C3=CC(Br)=CC=C3N/C2=NC(C4=CC(C)=NC(C5=C(N(N=C5)C)OCCC1)=C4)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– EGFR
Isoform
– EGFR/ErbB1/HER1
Pathway
– JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
