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Products Details
Product Description
– EGFR/BRAFV600E-IN-3 is a EGFR, BRAFV600E and EGFRT790M inhibitor with IC50 value of 57 nM, 68 nM and 9.70 nM. EGFR/BRAFV600E-IN-3 is an apoptotic inducer and also displays promising antioxidant activity[1].
Web ID
– HY-149518
Shipping
– Room temperature
Molecular Formula
– C25H18N4O3
References
– [1]El-Sheref EM, et al. Synthesis, Antioxidant and Antiproliferative Actions of 4-(1,2,3-Triazol-1-yl)quinolin-2(1H)-ones as Multi-Target Inhibitors. Int J Mol Sci. 2023 Aug 27;24(17):13300.
Molecular Weight
– 422.44
SMILES
– O=C1NC2=C(C=C(OC)C=C2)C(N3N=NC(C(C4=CC=CC=C4)=O)=C3C5=CC=CC=C5)=C1
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– Apoptosis;EGFR
Pathway
– Apoptosis;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
