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Product Description
– Eflornithine hydrochloride is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women.
Web ID
– HY-B0744A
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C6H13ClF2N2O2
References
– [1]Burri C, et al. Eflornithine for the treatment of human African trypanosomiasis. Parasitol Res. 2003 Jun;90 Supp 1:S49-52.|[2]Balfour JA, et al. Topical eflornithine. Am J Clin Dermatol. 2001;2(3):197-201; discussion 202.|[3]Kumar A, et al. A method to improve the efficacy of topical eflornithine hydrochloride cream. Drug Deliv. 2016 Jun;23(5):1495-501.|[4]Lipke DW, et al. Eflornithine alters changes in vascular responsiveness associated with coarctation hypertension. Clin Exp Hypertens. 1997 Apr;19(3):297-312.
CAS Number
– 68278-23-9
Molecular Weight
– 218.63
SMILES
– NC(CCCN)(C(F)F)C(O)=O.[H]Cl
Clinical Information
– Launched
Research Area
– Infection; Cancer
Solubility
– 10 mM in H2O
Target
– Parasite
Isoform
– Trypanosoma
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
