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Efflux inhibitor-1
$90 – $1,040
Products Details
Product Description
– Efflux inhibitor-1 (compound 2) is a pyrazolo[1,5-a]pyrimidine efflux inhibitor. Efflux inhibitor-1 selectively targets toward ABCG2/BCRP over ABCB1 with IC50s of 0.45 μM and 2.17 μM, respectively[1].
Web ID
– HY-112505
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Molecular Formula
– C28H25N5O3
References
– [1]Larson, et al. Selective efflux inhibitors and related pharmaceutical compositions and methods of treatment: United States, US9056111[P]. 2015-06-16.
CAS Number
– 1776055-29-8
Molecular Weight
– 479.53
Compound Purity
– 98.0
SMILES
– COC1=CC=CC=C1C2=NN(C(N3CCN(C(C4=COC=C4)=O)CC3)=CC(C5=CC=CC=C5)=N6)C6=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– BCRP
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
