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Products Details
Product Description
– EBI-1051 is a highly potent and orally efficacious MEK inhibitor with an IC50 of 3.9 nM.
Web ID
– HY-111368
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C18H15F2IN2O5
References
– [1]Lu B, et al. Discovery of EBI-1051: A novel and orally efficacious MEK inhibitor with benzofuran scaffold. Bioorg Med Chem. 2018 Feb 1;26(3):581-589.
CAS Number
– 1801896-05-8
Molecular Weight
– 504.22
SMILES
– O=C(NOC(CO)CO)C1=C(NC2=CC=C(I)C=C2F)C(F)=C3C(C=CO3)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– MEK
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
