Download Files:
Products Details
Product Description
– E67-2, as the E67 derivative, is a low-toxicity, selective KIAA1718 Jumonji domain inhibitor with an IC50 value of 3.4 µM. E67-2 selectively inhibits histone H3 lysine 9 (H3K9) Jumonji demethylase as well as histone H3 lysine 4 (H3K4) demethylase[1].
Web ID
– HY-122746
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H36N6O2
References
– [1] Upadhyay AK, et al. An analog of BIX-01294 selectively inhibits a family of histone H3 lysine 9 Jumonji demethylases. J Mol Biol. 2012;416(3):319-327.
CAS Number
– 1364914-62-4
Molecular Weight
– 404.55
SMILES
– CN(C)C1=C2C=C(OC)C(OCCCCCN)=CC2=NC(NCCCN(C)C)=N1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Histone Methyltransferase
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
