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Products Details
Product Description
– (E/Z)-NSAH is an isoform of NSAH (HY-114503), which is reversible and competitive nonnucleoside ribonucleotide reductase (RR) inhibitor, with cell-free IC50 of 32 μM and cell-based IC50 of ~250 nM, respectively[1].
Web ID
– HY-114503A
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C18H14N2O3
References
– [1]Md Faiz Ahmad, et al. Potent competitive inhibition of human ribonucleotide reductase by a nonnucleoside small molecule. Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):8241-8246.
CAS Number
– 54009-54-0
Molecular Weight
– 306.32
SMILES
– O=C(C1=CC=CC=C1O)N/N=C/C2=C3C=CC=CC3=CC=C2O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
