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Products Details
Product Description
– (E/Z)-HA155 is a potent autotaxin (ATX) type I inhibitor. (E/Z)-HA155 can be used for researching cancer, fibrotic diseases, inflammation, pain and angiogenesis[1].
Web ID
– HY-116100
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C24H19BFNO5S
References
– [1]Joncour A, et al. Discovery, Structure-Activity Relationship, and Binding Mode of an Imidazo[1,2-a]pyridine Series of Autotaxin Inhibitors [published correction appears in J Med Chem. 2018 May 10;61(9):4270]. J Med Chem. 2017;60(17):7371-7392.
CAS Number
– 1229652-22-5
Molecular Weight
– 463.29
SMILES
– OB(O)C1=CC=C(C=C1)COC2=CC=C(C=C2)/C=C(C3=O)SC(N3CC4=CC=C(C=C4)F)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Phosphodiesterase (PDE)
Isoform
– Autotaxin
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
