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(E)-C-HDMAPP (ammonium)
$334
Only 1000 item(s) left in stock.
Products Details
Product Description
– (E)-C-HDMAPP ammonium, is a potent phosphoantigen in ammonium form as well as a pyrophosphonate form of (E)-HDMAPP. (E)-C-HDMAPP is also an effective activator of γδ-T cells, induces T-cell stimulatory responses in vitro (EC50=0.91 nM for TNF-α release)[1][2].
Web ID
– HY-134950
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C6H23N3O7P2
References
– [1]Boëdec A, et al. Synthesis and biological activity of phosphonate analogues and geometric isomers of the highly potent phosphoantigen (E)-1-hydroxy-2-methylbut-2-enyl 4-diphosphate. J Med Chem. 2008 Mar 27;51(6):1747-54.
CAS Number
– 933030-60-5
Molecular Weight
– 311.21
SMILES
– OC/C(C)=C/CCP(OP(O)(O)=O)(O)=O.N.N.N
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– TNF Receptor
Isoform
– TNFRSF1A
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
