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Dyrk1A-IN-3
$590 – $4,800
Products Details
Product Description
– Dyrk1A-IN-3 (Compound 8b), a highly selective  dual-specificity tyrosine-regulated kinase 1A (DYRK1A) inhibitor, maintains high levels of DYRK1A binding affinity (IC50=76 nM). Dyrk1A-IN-3 can be used for the research of neurodegenerative disorders such as Alzheimer’s Disease, Huntington’s Disease, and Parkinson’s Disease[1].
Web ID
– HY-147060
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C18H16N6
References
– [1]Scott H Henderson, et al. Mining Public Domain Data to Develop Selective DYRK1A Inhibitors. ACS Med Chem Lett. 2020 Jun 30;11(8):1620-1626.
CAS Number
– 2493976-27-3
Molecular Weight
– 316.36
Compound Purity
– 99.96
SMILES
– CC1=CC(N(C)C2=NC(C3=C4C=CC=NN4N=C3)=CC=N2)=CC=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– DYRK
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
