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DX3-213B
$280 – $2,160
Products Details
Product Description
– DX3-213B is a highly potent, orally active oxidative phosphorylation (OXPHOS) complex I inhibitor (IC50=3.6 nM). DX3-213B impairs ATP generation (IC50=11 nM), and blocks MIA PaCa-2 cell growth (GI50=11 nM). DX3-213B is used for the research of the pancreatic cancer[1].
Web ID
– HY-144310
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C20H28F2N2O5S2
References
– [1]Xue D, et al. Multiparameter Optimization of Oxidative Phosphorylation Inhibitors for the Treatment of Pancreatic Cancer. J Med Chem. 2022;65(4):3404-3419.
CAS Number
– 2749555-66-4
Molecular Weight
– 478.57
Compound Purity
– 99.76
SMILES
– O=S(N1C[C@@H](CCC1)C(N2CCC(F)(CC2)F)=O)(C3=CC=C(C=C3)S(C(C)C)(=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 125 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Mitochondrial Metabolism
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
