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DX2-201
SKU
HY-145303-Get quote
Category Reference compound
Tags Cancer, Metabolic Enzyme/Protease, Mitochondrial Metabolism
Products Details
Product Description
– DX2-201 is a potent and selective oxidative phosphorylation (OXPHOS) complex I inhibitor with an IC50 of 312 nM. DX2-201 has anticancer effects[1].
Web ID
– HY-145303
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C18H28N2O6S2
References
– [1]Ding Xue, et al. Discovery and Lead Optimization of Benzene-1,4-disulfonamides as Oxidative Phosphorylation Inhibitors.J Med Chem. 2022 Jan 13;65(1):343-368. https://pubmed.ncbi.nlm.nih.gov/34982568/
CAS Number
– 2749554-00-3
Molecular Weight
– 432.55
SMILES
– O=S(N1C[C@@H](CCC1)C(OCC)=O)(C2=CC=C(C=C2)S(N(CC)CC)(=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Mitochondrial Metabolism
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.