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Products Details
Product Description
– Duocarmycin GA is an antibody agent conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. Duocarmycin GA can be used against multi-agent resistant cell lines.
Web ID
– HY-128873
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C26H25ClN4O3
References
– [1]Searcey M. Duocarmycins–natures prodrugs? Curr Pharm Des. 2002;8(15):1375-89.
CAS Number
– 1613286-59-1
Molecular Weight
– 476.95
SMILES
– O=C(NC1=CC2=C(C=C1)C=C(C(N3C[C@@H](CCl)C4=C3C=C(O)C5=CC=CC=C45)=O)N2)CN(C)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Cytotoxin;DNA Alkylator/Crosslinker
Isoform
– Duocarmycins
Pathway
– Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage
Product type
– ADC Related
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
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