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DSP-1053
$590 – $4,800
Products Details
Product Description
– DSP-1053, a benzylpiperidine derivative, is a potent Serotonin Transporter (SERT) inhibitor with a Ki of 1.02 nM. DSP-1053 shows partial 5-HT1A receptor agonistic activity with a Ki of 5.05 nM. DSP-1053 has antidepressant activity[1].
Web ID
– HY-111419
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C26H32BrNO4
References
– [1]Yoshinaga H, et al. Discovery of DSP-1053, a novel benzylpiperidine derivative with potent serotonin transporter inhibitory activity and partial 5-HT1A receptor agonistic activity. Bioorg Med Chem. 2018 May 1;26(8):1614-1627.
CAS Number
– 1176326-76-3
Molecular Weight
– 502.44
Compound Purity
– 99.72
SMILES
– BrC1=CC=C(CC2CCN(CCC3=CC(C(CCO4)=O)=C4C=C3)CC2)C=C1OCCOC
Clinical Information
– Phase 1
Research Area
– Neurological Disease
Solubility
– DMSO : 200 mg/mL (ultrasonic)
Target
– 5-HT Receptor;Serotonin Transporter
Isoform
– 5-HT1 Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
