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Products Details
Product Description
– DSHN is a potent small heterodimer partner (SHP) activator. DSHN inhibits Ccl2 expression and secretion by inhibiting p65 activation of Ccl2 promoter activity. DSHN can be used in research of cancer[1].
Web ID
– HY-121896
Shipping
– Room temperature
Molecular Formula
– C15H17NO5S
References
– [1]Yang Z, et, al. A Novel Small Molecule Activator of Nuclear Receptor SHP Inhibits HCC Cell Migration via Suppressing Ccl2. Mol Cancer Ther. 2016 Oct;15(10):2294-2301.
CAS Number
– 313952-63-5
Molecular Weight
– 323.36
SMILES
– O=C(O)C1=C(C=C2C(S(=O)(N(CC)CC)=O)=CC=CC2=C1)O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– SHP2
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
