DS08210767

$650$3,900

Products Details

Product Description

– DS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with IC50 of 90 nM[1].

Web ID

– HY-125879

Storage Temperature

– -20°C, 3 years (Powder)

Shipping

– Blue Ice

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C31H39N5O2

References

– [1]Arai Y, et al. Discovery of novel PTHR1 antagonists: Design, synthesis, and structure activity relationships. Bioorg Med Chem Lett. 2019 Sep 15;29(18):2613-2616.

CAS Number

– 2376334-75-5

Molecular Weight

– 513.67

Compound Purity

– 99.75

SMILES

– CC1(N=C(C2=CC=C(C=C2N(C1=O)C3=CC=C(C=C3)NCCNC4CCOCC4)C#N)C5CCCCC5)C

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease; Endocrinology

Solubility

– DMSO : 5 mg/mL (ultrasonic;warming;heat to 80°C)

Target

– Thyroid Hormone Receptor

Pathway

– Vitamin D Related/Nuclear Receptor

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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