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DS08210767
$650 – $3,900
Products Details
Product Description
– DS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with IC50 of 90 nM[1].
Web ID
– HY-125879
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C31H39N5O2
References
– [1]Arai Y, et al. Discovery of novel PTHR1 antagonists: Design, synthesis, and structure activity relationships. Bioorg Med Chem Lett. 2019 Sep 15;29(18):2613-2616.
CAS Number
– 2376334-75-5
Molecular Weight
– 513.67
Compound Purity
– 99.75
SMILES
– CC1(N=C(C2=CC=C(C=C2N(C1=O)C3=CC=C(C=C3)NCCNC4CCOCC4)C#N)C5CCCCC5)C
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease; Endocrinology
Solubility
– DMSO : 5 mg/mL (ultrasonic;warming;heat to 80°C)
Target
– Thyroid Hormone Receptor
Pathway
– Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
