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DS-1001b
SKU
HY-129545-10 mg
Category Reference compound
Tags Cancer, Isocitrate Dehydrogenase (IDH), Metabolic Enzyme/Protease
$90 – $750
Products Details
Product Description
– DS-1001b is a mutant IDH-1 (Isocitrate Dehydrogenase-1) inhibitor extracted from patent WO2016052697A1, Example 168, and has antitumor activity[1].
Web ID
– HY-129545
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C29H29Cl3FN3O4
References
– [1]Zhao Yizhaiteng, et al. Isoxazole derivative as mutated isocitrate dehydrogenase 1 inhibitor. WO2016052697A1.
CAS Number
– 1898207-64-1
Molecular Weight
– 608.92
Compound Purity
– 99.71
SMILES
– CC(C)(N)C.O=C(N1C2=CC=CC(/C=C/C(O)=O)=C2C(C)=C1)C3=C(C(C)(F)C)ON=C3C4=C(C=C(Cl)C=C4Cl)Cl
Clinical Information
– Phase 2
Research Area
– Cancer
Solubility
– DMSO : 29 mg/mL (ultrasonic)
Target
– Isocitrate Dehydrogenase (IDH)
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.