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Product Description
– Drotrecogin alfa activated (DrotAA) is recombinant human activated protein C (APC). Drotrecogin alfa activated prevents smoke-induced increases in pulmonary microvascular permeability and proinflammatory cytokine IL-1β in rats. Drotrecogin alfa activated inhibits coagulation and inflammation and promotes fibrinolysis. Drotrecogin alfa activated can be used for severe sepsis reaearch[1][2].
Web ID
– HY-112956
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– N/A
References
– [1]Lyseng-Williamson KA, et al. Drotrecogin alfa (activated). Drugs. 2002;62(4):617-30; discussion 631-2.|[2]Wong SS, et al. Drotrecogin alfa (activated) prevents smoke-induced increases in pulmonary microvascular permeability and proinflammatory cytokine IL-1beta in rats. Lung. 2004;182(6):319-30.
CAS Number
– 98530-76-8
Molecular Weight
– N/A
SMILES
– [Drotrecogin alfa (activated)]
Clinical Information
– Launched
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Others
Pathway
– Others
Product type
– Inhibitory Antibodies
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
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