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Drotaverine (hydrochloride)
SKU
HY-108974-10 mg
Category Reference compound
Tags Calcium Channel;Phosphodiesterase (PDE), Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling
$60 – $550
Products Details
Product Description
– Drotaverine (hydrochloride) is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor and an L-type voltage-dependent calcium channel (L-VDCC) blocker, blocks the degradation of 3′,5′-cyclic adenosine monophosphate. Drotaverine (hydrochloride) exhibits in vivo antispasmodic efficacy without anticholinergic effects.
Web ID
– HY-108974
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C24H32ClNO4
References
– [1]Patai Z, Guttman A, Mikus EG. Assessment of the Airway Smooth Muscle Relaxant Effect of Drotaverine. Pharmacology. 2018;101(3-4):163-169.
CAS Number
– 985-12-6
Molecular Weight
– 433.97
Compound Purity
– 99.48
SMILES
– CCOC1=CC2=C(C=C1OCC)CCN/C2=CC3=CC=C(OCC)C(OCC)=C3.[H]Cl
Clinical Information
– Launched
Solubility
– H2O : 100 mg/mL (ultrasonic)
Target
– Calcium Channel;Phosphodiesterase (PDE)
Isoform
– L-type calcium channel;PDE4
Pathway
– Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling
Product type
– Reference compound
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