Drotaverine (hydrochloride)

$60$550

Products Details

Product Description

– Drotaverine (hydrochloride) is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor and an L-type voltage-dependent calcium channel (L-VDCC) blocker, blocks the degradation of 3′,5′-cyclic adenosine monophosphate. Drotaverine (hydrochloride) exhibits in vivo antispasmodic efficacy without anticholinergic effects.

Web ID

– HY-108974

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C24H32ClNO4

References

– [1]Patai Z, Guttman A, Mikus EG. Assessment of the Airway Smooth Muscle Relaxant Effect of Drotaverine. Pharmacology. 2018;101(3-4):163-169.

CAS Number

– 985-12-6

Molecular Weight

– 433.97

Compound Purity

– 99.48

SMILES

– CCOC1=CC2=C(C=C1OCC)CCN/C2=CC3=CC=C(OCC)C(OCC)=C3.[H]Cl

Clinical Information

– Launched

Solubility

– H2O : 100 mg/mL (ultrasonic)

Target

– Calcium Channel;Phosphodiesterase (PDE)

Isoform

– L-type calcium channel;PDE4

Pathway

– Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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