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Products Details
Product Description
– DprE1-IN-9 (compound B18) is an effective reversible DprE1 inhibitor and can bind to the receptor cavity of DprE1. DprE1-IN-9 shows strong antimycobacterial activity not only against non-pathogenic strain H37Ra (MIC=0.18 µg/mL) but also against pathogenic H37Rv and the clinical MDR and XDR isolates[1].
Web ID
– HY-149581
Shipping
– Room temperature
Molecular Formula
– C22H25F3N4O2
References
– [1]Wang Xiang, et al. Discovery of novel reversible inhibitor of DprE1 based on benzomorpholine for the treatment of tuberculosis. Microbiol Spectr. 2023 Sep 12:e0472122.
CAS Number
– 2906099-98-5
Molecular Weight
– 434.45
SMILES
– O=C(C1=C2OCCN(CC3=NC(C)=C(C)N=C3C)C2=CC(C4CC4)=C1)NCC(F)(F)F
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
