DPQ

$110$990

Products Details

Product Description

– DPQ is a potent PARP-1 inhibitor. DPQ can reduce the N-methyl-d-aspartate (NMDA)-induced PARP activation, restoring ATP to near control levels and significantly attenuating neuronal injury in the severe NMDA exposure model. DPQ can be used for researching neuroprotection[1].

Web ID

– HY-114869

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Neuroscience-Neurodegeneration

Molecular Formula

– C18H26N2O2

References

– [1]Meli E, et al. Differential role of poly(ADP-ribose) polymerase-1in apoptotic and necrotic neuronal death induced by mild or intense NMDA exposure in vitro. Mol Cell Neurosci. 2004;25(1):172-180.

CAS Number

– 129075-73-6

Molecular Weight

– 302.41

Compound Purity

– 99.0

SMILES

– O=C1C2=C(CCN1)C(OCCCCN3CCCCC3)=CC=C2

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– PARP

Pathway

– Cell Cycle/DNA Damage;Epigenetics

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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