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Dp44mT
$32 – $240
Products Details
Product Description
– Dp44mT is an iron chelator with selective anticancer activity.
Web ID
– HY-18973
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C14H15N5S
References
– [1]Rao VA, et al. The iron chelator Dp44mT causes DNA damage and selective inhibition of topoisomerase IIalpha in breast cancer cells. Cancer Res. 2009 Feb 1;69(3):948-57.|[2]Lovejoy DB, et al. Antitumor activity of metal-chelating compound Dp44mT is mediated by formation of a redox-active copper complex that accumulates in lysosomes. Cancer Res. 2011 Sep 1;71(17):5871-80.
CAS Number
– 152095-12-0
Molecular Weight
– 285.37
Compound Purity
– 98.0
SMILES
– S=C(N/N=C(C1=NC=CC=C1)C2=NC=CC=C2)N(C)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Apoptosis;Ferroptosis
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
