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Dox-btn2
$1,100
Only 1000 item(s) left in stock.
Products Details
Product Description
– Dox-btn2 is a biotinylated derivative of Doxorubicin (HY-15142A), with a biotin label at the point of conjugation to doxorubicin at 3′-NH2. Dox-btn2 can be used for cell imaging. While Doxorubicin is mainly accumulated in the nucleus, while Dox-btn2 is mainly located in the cytoplasm[1].
Web ID
– HY-153797
Storage Temperature
– -20°C (Powder, protect from light)
Shipping
– Blue Ice
Molecular Formula
– C48H64N4O18S
References
– [1]Yu Z, et al. Chem-map profiles drug binding to chromatin in cells. Nat Biotechnol. 2023 Jan 23.
Molecular Weight
– 1017.10
Compound Purity
– 95.0
SMILES
– O=C1C2=C(O)C3=C([C@H](C[C@](C(CO)=O)(C3)O)O[C@H]4C[C@H](NC(CCOCCOCCOCCOCCNC(CCCC[C@H]5[C@@]6([H])NC(N[C@]6(CS5)[H])=O)=O)=O)[C@H](O)[C@H](C)O4)C(O)=C2C(C7=C1C=CC=C7OC)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection
Solubility
– 10 mM in DMSO
Target
– ADC Cytotoxin;AMPK;Antibiotic;Apoptosis;Autophagy;Bacterial;HBV;HIV;Mitophagy;Topoisomerase
Pathway
– Antibody-drug Conjugate/ADC Related;Anti-infection;Apoptosis;Autophagy;Cell Cycle/DNA Damage;Epigenetics;PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
