Dovitinib-RIBOTAC

SKU HY-139682-1 mg Category Tags , ,

$400$4,250

Products Details

Product Description

– Dovitinib RIBOTAC is a targeted RNA degrader that cleaves pre-miR-21 with enhanced potency and selectivity.

Web ID

– HY-139682

Storage Temperature

– -20°C (Powder, protect from light, stored under nitrogen)

Shipping

– Blue Ice

Applications

– Cancer-programmed cell death

Molecular Formula

– C51H56FN9O10S

References

– [1]Zhang P, et al. Reprogramming of Protein-Targeted Small-Molecule Medicines to RNA by Ribonuclease Recruitment. J Am Chem Soc. 2021 Aug 25;143(33):13044-13055.

CAS Number

– 2759351-68-1

Molecular Weight

– 1006.11

Compound Purity

– 98.93

SMILES

– O=C1C(C2=NC3=CC(N4CCN(CCNC(NCCOCCOCCOCCOC5=C(O)C=C(/C=C6C(C(C(OCC)=O)=C(NC7=CC=CC=C7)S/6)=O)C=C5)=O)CC4)=CC=C3N2)=C(N)C8=C(C=CC=C8F)N1

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 130 mg/mL (ultrasonic)

Target

– PROTACs

Isoform

– Cereblon

Pathway

– PROTAC

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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