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Doramectin
$65 – $110
Products Details
Product Description
– Doramectin is a derivative of Ivermectin (HY-15310). Doramectin is a potent antiparasitic antibiotic. Doramectin is an active compound against S.mansoni in an NMRI mouse infection model[1][2][3].
Web ID
– HY-17035
Storage Temperature
– -20°C (Powder, protect from light)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C50H74O14
References
– [1]Davey RB, Pound JM, Klavons JA, Lohmeyer KH, Freeman JM, Olafson PU.
Analysis of doramectin in the serum of repeatedly treated pastured cattle used to predict the probability of cattle fever ticks (Acari: Ixodidae) feeding to repletion.
Exp Appl Acarol. 2012 Apr;56(4):365-74. doi: 10.1007/s10493-012-9525-1.|[2]Wang XJ, Zhang J, Wang JD, Huang SX, Chen YH, Liu CX, Xiang WS.
Four new doramectin congeners with acaricidal and insecticidal activity from Streptomyces avermitilis NEAU1069.
Chem Biodivers. 2011 Nov;8(11):2117-25. doi: 10.1002/cbdv.201000295.|[3]Gordana Panic, et al. Activity Profile of an FDA-Approved Compound Library against Schistosoma mansoni. PLoS Negl Trop Dis. 2015 Jul 31;9(7):e0003962.
CAS Number
– 117704-25-3
Molecular Weight
– 899.11
Compound Purity
– 98.83
SMILES
– CO[C@@H]1[C@@H](O[C@]2([H])O[C@@H](C)[C@H](O)[C@@H](OC)C2)[C@H](C)O[C@@]([H])(O[C@H](/C(C)=C/C[C@]3([H])C[C@]([H])(OC4=O)C[C@]5(C=C[C@H](C)[C@@H](C6CCCCC6)O5)O3)[C@@H](C)/C=C/C=C7CO[C@@]8([H])[C@]7(O)[C@@]4([H])C=C(C)[C@H]8O)C1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– DMSO : ≥ 50 mg/mL
Target
– Antibiotic;Bacterial;Parasite
Pathway
– Anti-infection
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
