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Product Description
– Dopamine D3 receptor ligand-4 (compound 6) is a potent and selective dopamine D3 receptor ligand, with a Ki of 0.5 nM. Dopamine D3 receptor ligand-4 shows high level of selectivity for D3 over D2 (Ki=7.43 nM)[1].
Web ID
– HY-115968
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C26H28N4OS
References
– [1]Blass BE, et al. Design, synthesis, and evaluation of functionalized 5-(4-arylpiperazin-1-yl)-N-arylpentanamides as selective dopamine D3 receptor ligands. Med Chem Res 31, 132-145 (2022).
CAS Number
– 2376333-77-4
Molecular Weight
– 444.59
SMILES
– O=C(NCCCCN1CCN(C2=CC=CC(C#N)=C2)CC1)C3=CC=C(C4=CSC=C4)C=C3
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Dopamine Receptor
Isoform
– D2 Receptor;D3 Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
