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Products Details
Product Description
– Dopamine D3 receptor ligand-2 (compound 8) is a potent D3 receptor ligand with a Ki of 11.4 nM. Dopamine D3 receptor ligand-2 have high selectivity for D3 over D2 (Ki=1228 nM)[1].
Web ID
– HY-115954
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C27H29N5O
References
– [1]Benjamin E. Blass, et al. Synthesis of functionalized 5-(4-arylpiperazin-1-yl)-N-arylpentanamides and their evaluation as D3 receptor ligands. Medicinal Chemistry Research volume 31, pages735–748 (2022).
CAS Number
– 2882828-95-5
Molecular Weight
– 439.55
SMILES
– N#CC1=CC(N2CCN(CC2)CCCCC(NC3=CC=C(C=C3)C4=NC=CC=C4)=O)=CC=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Dopamine Receptor
Isoform
– D2 Receptor;D3 Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
